Recent Blog Posts
Image Alt

Meet Dr. Paul Despres

Dr. Paul Despres, ND, FAAO

Licensed Naturopathic Physician
Fellow of the American Academy of Ozonotherapy
Co-Owner

About Dr. Paul

Dr. Paul Despres is a compassionate naturopathic medical doctor with expertise in a wide range of natural, conventional, and advanced therapies for both acute and chronic conditions. As a co-owner of Aspen Integrative Medical Center with his wife, Dr. Alexandra Mele, Dr. Despres is deeply committed to providing an exceptional patient care experience that addresses the root causes of illness, empowers patients to achieve optimal health, and promotes disease prevention.

Having personally navigated complex chronic diseases such as juvenile arthritis, autoimmune disease, and gastrointestinal disorders, Dr. Despres is able to empathize with his patients’ struggles. As a physician, he is dedicated to:

– Taking the time to listen, understand, and build meaningful relationships with his patients

– Providing an accurate and thorough diagnosis, and helping patients fully understand their conditions and symptoms

– “Meeting patients where they are,” tailoring testing and treatment plans to individual needs, personalities, and financial considerations

– Offering innovative, root-cause treatments to address underlying health issues

– Creating personalized treatment plans, rather than relying on standardized protocols

– Responding promptly and reliably to patients’ concerns

"I am committed to researching new healing methods and designing innovative, effective treatment plans tailored to each patient. My goal is not only to help patients recover and prevent illness, but also to guide them toward a healthier mind, body, and spirit. I listen attentively, focusing on the details, so that my patients can live life to the fullest."

Areas of Focus

Clinical Skills

Education and Training

  • University of Michigan, Ann Arbor, MI – Bachelor of Arts, 2008
  • Bellevue Massage School, Bellevue, WA – License in Massage Therapy, 2013
  • Bastyr University, Kenmore, WA – Doctorate in Naturopathic Medicine, 2016
  • Mold Literate Doctor with Dr. Jill Crista Training, 2019
  • Lyme Literate Doctor with ILADS Training, 2021
  • Certified in Ozonotherapy, American Academy of Ozonotherapy, 2024
  • Certified in Advanced Prolozone, American Academy of Ozonotherapy, 2024
  • Fellow of the American Academy of Ozonotherapy, 2025-Present
  • Certified in EBOO, Detox, and Drainage, 2025
  • Certified in Neural Therapy, 2026

Memberships

Hear what patients have to say about Dr. Paul

Dianna S
March 3, 2026
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Dr Despres is kind, skilled, and thoughtful. The office staff and helpful and professional. They have treatments are are difficult to find elsewhere, and a non toxic office environment.
Andy P
February 18, 2026
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
There isn’t a better doctor in Flagstaff. Have had many issues finding a medical home until now. Many thanks to the Aspen group for being so very amazing!
Jt
January 8, 2026
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Great place! Finally a doctor who doesn’t just have you in and out and make you feel like a number. They saw me for over a whole hour and listened to everything I had to say for my cancer treatment and therapy, also did the hyperbaric oxygen therapy which not only was affordable but also went really well and felt good during the entire process. Best place I’ve been to in a while
Debbie C
September 16, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
I’m one of those people who doesn’t believe in accidents anymore. I truly feel I was Divinely guided to find this amazing place, where I can fully entrust my health to the entire staff. The energy here is gentle and welcoming, and the facility is clean and peaceful. Drs. Mele and Despres are not only kind, compassionate, and understanding, but also highly knowledgeable and professional. They take the time to find the best approach to help each individual regain health, strength, and even confidence. I can’t express enough how grateful and happy I am to have found this place. I drive all the way from Sedona, but every minute on the road is absolutely worth it.
Bruce C
September 16, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
I have had pain on the left side of my right knee for about 10 years. Two years ago I had an MRI that showed no structural damage to the knee but it still hurt. I went to see Dr Despres at Aspen Integrative and he recommended Prolozone therapy. I researched it and it sounded like a good option so I had an injection. Immediately after the injection the pain is gone and it generally last for 3 to 4 months but I understand it could heal completely.
Christine W
September 4, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Dr. Despres at Aspen Integrative is the best doctor I’ve ever had. He truly listens and always meets me where I’m at. What I appreciate most is that he lets me take an active role in my own protocol instead of just telling me what to do. It feels like a partnership in my care, which is rare to find. Jane, the medical assistant, is also wonderful! I always leave feeling heard, respected, and supported. I can’t recommend them highly enough!
Laura T
August 22, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Both practitioners are very kind and very knowledgeable in the field. I have been having treatment for 8 years and thought I knew it all. They have introduced some new treatments for me and my family to try and we are actually seeing improvements. Encouraging us to start with good support to my system is the priority over harsh treatments protocols our bodies can’t handle. Dr Mele is great with my children and really hears them and helps get to the root.
Casey C
April 28, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Flagstaff is lucky to have a resource like this! Dr. Mele and Dr. Despres deliver a rare combination of compassionate care and cutting-edge therapies, including ozone therapy, hyperbaric oxygen, sauna sessions, and vibration plate treatments. Their holistic approach also weaves in botanical medicine, homeopathy, visceral manipulation, craniosacral therapy, and thorough lab analysis — truly addressing the whole person. They take the time to understand each patient's history, needs, and goals, offering a level of care that's both modern and deeply healing. I wouldn’t hesitate to recommend them to my own family. If you’re looking for a team that blends the latest science with skilled, heart-centered healing, you’ll find it here.
Kim M
February 18, 2025
Google star 1Google star 2Google star 3Google star 4Google star 5Trustindex verifies that the original source of the review is Google.
Dr. Paul Despres has literally changed my life! I had horrible undiagnosed gut issues, and after meeting with two gastroenterologists that were not able to diagnose the problem, I found Dr. Paul. He put me on a regimen of supplements to help me with my gut, and proceeded to work with me also on vitamin deficiencies and my osteoporosis. The result has been a complete reduction of all gut symptoms (turned out I had SIBO), and a significantly better energy level and quality of life thanks to Dr. Paul. A special shout out to his lovely and competent assistant Jane. She is whip smart and always responsive. I highly recommend Aspen Integrative Medical Center.

Schedule an appointment with Dr. Despres.