Recent Blog Posts
Image Alt

About Our Clinic

About Our Clinic

Let us introduce ourselves.

Aspen Integrative Medical Center is a well-established, full-service clinic in downtown Flagstaff, Arizona, offering high-quality integrative medicine since 2017. We blend the latest medical research and cutting-edge therapies with traditional naturopathic modalities to help our patients feel their best. Our holistic approach considers the “whole you”—mind, body, and soul—creating personalized treatment plans that support your overall health and well-being.

Become a patient today and join a community of like-minded individuals who prioritize their health just as much as you do!

Our History

Our clinic is a family practice at heart, owned and operated by husband-and-wife duo Dr. Paul Despres and Dr. Alexandra Mele, who purchased the clinic in 2024.

Dr. Despres and Dr. Mele first met at Bastyr University’s Naturopathic Medicine Program in Kenmore, WA, where they discovered a shared dream—to create a one-of-a-kind clinic that transforms lives. Their journey took them from the Pacific Northwest to the Arizona desert, where Dr. Mele completed a two-year teaching residency at Sonoran University of Health Sciences in Tempe. After her residency, they moved to Flagstaff to turn their vision into reality and establish deep roots in the community.

Today, they are honored to serve the Flagstaff community, committed to increasing access to the healing benefits of naturopathic medicine.

The Aspen Difference

At Aspen, we hold ourselves to the highest standard of personalized care—offering a unique approach you won’t find elsewhere. We understand that true healing goes beyond treatments, therapies, and procedures. From your first phone call to the atmosphere of our treatment rooms, every interaction is part of the care we provide. Your health and well-being are our top priorities, and we work tirelessly to ensure you feel seen, heard, and valued by both our physicians and staff. That is the ‘Aspen Difference.’

Our Mission

Our mission is to foster a healthier community through naturopathic medicine, promoting root-cause healing, disease prevention, and optimal wellness. We achieve this by providing individualized patient care, unparalleled medical services, and empowering health education.

Our Vision

We are committed to improving the lives of those facing illness while empowering individuals with the tools and knowledge to achieve lifelong health and wellness.

About Our Space

Our medical center is located downtown Flagstaff, AZ. Our center consists of:

– Warm reception area with complimentary herbal tea and snacks
– Three naturopathic physician offices
IV ozone therapy suite for hemalumen IV ozone, EBOO, and multi-pass
Advanced IV therapy suite
Hyperbaric oxygen chamber suite
Neurofeedback suite
VibePlate and physical exam room
– Full-service blood draw and processing lab
– Large supplement and botanical medicine dispensary
– Easy wheelchair and handicap access

“Every time I am at Aspen I feel like I’m at home. The support staff and physicians have always taken such great care of myself and my family.”

~ C.P.

Excellent rating
Based on 79 reviews
Google star 1Google star 2Google star 3Google star 4Google star 5
Google star 1Google star 2Google star 3Google star 4Google star 5
A year ago I was extremely sick. Didn’t know if I was going to make it to see another year. I was diagnosed with pots put on numerous medication’s that I did not need from a different doctor, but once I started getting seen by doctor.Mele At Aspen integrative it completely changed my life. I am 1000 times better than I was a year ago my hair which had fallen out completely his back and down to my I feel great and I love life again if you ever have the opportunity or chance to get seen by any of these doctors, I highly suggested Thank you guys for all that you do
Christina O
6 April 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
I have been seeing Dr. Mele since the summer of 2025 to help treat some complex health issues, and I am so grateful I found her! She is kind, thorough, patient and her treatment protocols are both gentle and effective! I have felt heard, understood, and supported every step of the way, and finally see light at the end of a tunnel. Her staff is also very kind and responsive, making the whole experience incredibly supportive - cannot recommend Aspen Integrative Medical Center enough.
Jenna G
3 March 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Dr Despres is kind, skilled, and thoughtful. The office staff and helpful and professional. They have treatments are are difficult to find elsewhere, and a non toxic office environment.
Dianna S
3 March 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
I’m grateful to have found Aspen Integrative Medical Center. Dr. Mele is so kind, attentive, and knowledgeable. Jane, Amelia, and Nurse Aaron are professional and genuinely caring. Recently, I contracted pneumonia and went to the office for an acute visit. I was able to have my bloodwork done there in the clinic and Dr. Mele responded with a balanced approach by prescribing needed conventional medicines as well as natural remedies. My husband was with me and was so impressed with the whole experience that he said he would rather pay more to go there than go to a regular clinic. I couldn’t agree more.
Catherine H
3 March 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
There isn’t a better doctor in Flagstaff. Have had many issues finding a medical home until now. Many thanks to the Aspen group for being so very amazing!
Andy P
18 February 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
I started seeing Dr. Mele in November. I was feeling pretty low and stressed about ongoing stomach issues that I couldn’t figure out. This is my first experience working with a naturopath and it’s been a process. But I can feel things shifting in me. It feels like we are excavating some deeper issues, so other symptoms have been popping up, but I have been experiencing definite progress. It’s a wholistic experience, not a quick fix. I’ve been doing a lot of emotional processing along the way and allowing myself to be right where I am at. I am grateful for Dr. Mele - her knowledge, wisdom and compassion. This has all felt very vulnerable and I feel like I have a true ally in the process. Highly recommend.
The S
13 January 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Great place! Finally a doctor who doesn’t just have you in and out and make you feel like a number. They saw me for over a whole hour and listened to everything I had to say for my cancer treatment and therapy, also did the hyperbaric oxygen therapy which not only was affordable but also went really well and felt good during the entire process. Best place I’ve been to in a while
Jt
8 January 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Update: I received more answers with Dr. Mele in 30 minutes than I did at the ER on New Year’s Eve. It’s been 24 hours and I am feeling so much better. Not sure what this evil virus/sickness is that’s going around, but what Dr. Mele did and prescribed has helped immensely. And I super appreciate the fact that I was able to bring my health advocate (the spouse) and that was welcomed. We all need support and for that support to be honored. Go to Aspen if you want to be treated like a real human and not just another insurance claim. After 10 years of being ignored, I am finally getting answers and treatment. If you are tired of being put in a box, misdiagnosed, and told it's all in your head, you need Aspen. Professional, kind, caring, and well educated with verifiable resources...I am so happy I found Apsen! Thank you to the staff and Doctor Mele for doing what you do, the world needs more people like you!
Trista R
8 January 2026
Google star 1Google star 2Google star 3Google star 4Google star 5
Really appreciate the time, attention, care and the thoroughness of each session, including the follow-ups and communication. Thank you!
Kim S
17 December 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I highly recommend Dr. Mele. I have received craniosacral therapy from Dr. Mele and I found it to be very helpful for structural relief and relaxation. As a local practitioner, I have also referred patients to her and they have had great experiences with her care. She is thorough and thoughtful and has many tools to care for people. I will continue to send patients her way.
Betsy D
23 October 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Dr. Mele is very knowledgeable. She is compassionate and responsive to requests. Great Doc!!
Merri L
8 October 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I’m one of those people who doesn’t believe in accidents anymore. I truly feel I was Divinely guided to find this amazing place, where I can fully entrust my health to the entire staff. The energy here is gentle and welcoming, and the facility is clean and peaceful. Drs. Mele and Despres are not only kind, compassionate, and understanding, but also highly knowledgeable and professional. They take the time to find the best approach to help each individual regain health, strength, and even confidence. I can’t express enough how grateful and happy I am to have found this place. I drive all the way from Sedona, but every minute on the road is absolutely worth it.
Debbie C
16 September 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I have had pain on the left side of my right knee for about 10 years. Two years ago I had an MRI that showed no structural damage to the knee but it still hurt. I went to see Dr Despres at Aspen Integrative and he recommended Prolozone therapy. I researched it and it sounded like a good option so I had an injection. Immediately after the injection the pain is gone and it generally last for 3 to 4 months but I understand it could heal completely.
Bruce C
16 September 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Dr. Despres at Aspen Integrative is the best doctor I’ve ever had. He truly listens and always meets me where I’m at. What I appreciate most is that he lets me take an active role in my own protocol instead of just telling me what to do. It feels like a partnership in my care, which is rare to find. Jane, the medical assistant, is also wonderful! I always leave feeling heard, respected, and supported. I can’t recommend them highly enough!
Christine W
4 September 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Aspen Integrative is such a great environment for healing. Dr. Mele has helped me with longer term gut and skin issues as well as COVID and shorter term sickness, and I've always felt very supported!
Luke A
25 August 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Both practitioners are very kind and very knowledgeable in the field. I have been having treatment for 8 years and thought I knew it all. They have introduced some new treatments for me and my family to try and we are actually seeing improvements. Encouraging us to start with good support to my system is the priority over harsh treatments protocols our bodies can’t handle. Dr Mele is great with my children and really hears them and helps get to the root.
Laura T
22 August 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I have been to many different specialist and had various lab work and test done all for Doctors to tell me they have no idea what’s going on with me. I’ve had doctors tell me my symptoms are all in my head and I am perfectly fine. I’ve had doctors tell me I need anxiety medicine or depression medicine. Dr. Mele was the first Doctor who really listened to me. For the first time in forever I am finally feeling more like myself! Aspen Integrative Medical Center and Dr. Mele have been a life saver!
Brittany B
16 June 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Flagstaff is lucky to have a resource like this! Dr. Mele and Dr. Despres deliver a rare combination of compassionate care and cutting-edge therapies, including ozone therapy, hyperbaric oxygen, sauna sessions, and vibration plate treatments. Their holistic approach also weaves in botanical medicine, homeopathy, visceral manipulation, craniosacral therapy, and thorough lab analysis — truly addressing the whole person. They take the time to understand each patient's history, needs, and goals, offering a level of care that's both modern and deeply healing. I wouldn’t hesitate to recommend them to my own family. If you’re looking for a team that blends the latest science with skilled, heart-centered healing, you’ll find it here.
Casey C
28 April 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I am very pleased with my experience with Dr. Mele .. She has been kind, thorough and present.. i felt listened to and she had clearly read my profile before our first meeting.. She is very knowledgeable regarding Thyroid disease and is helpful on helping me understand this complicated disease… i look forward to working with her and getting some really positive results.. Jane @ front desk is very pleasant and helpful i recommend this practice and i am thrilled to have them in Flagstaff🌷
Juliana B
24 April 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I can't express enough how happy I am to have found Aspen Integrative Medicine and Dr. Mele. A few months ago I had a lightbulb moment and connected 34 years of issues and it became very clear to me I might have a specific disorder. I wanted to go through insurance at the time, but after speaking to Dr. Mele on the phone it became so clear to me time is money, and you can't put a price on the value of being heard and taken seriously. She didn't get offended or challenged when I walked in with ideas and thoughts of my own health issues, she listened and validated and was quick to confirm what I already knew. I am so grateful of her approach and willingness to being a team when it comes to my health, and offering new perspectives and strategies to tackle my concerns. I trust her completely and am so grateful to have such quality care, especially in a small town.
Erin T
6 March 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I have a rather rare autoimmune illness, and I am being treated here in the hopes that I feel better. The Doctor is excellent and so is his staff. I have also started hyperbaric treatments. You do spend some money here because insurance doesn't cover it. That's going to be the only downside for me. Since I am retired.
Debra C
26 February 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
I have nothing but wonderful things to say about this place! All staff members are incredible to work with and I cannot recommend them enough! Health journeys are always scary and unpredictable at times but the support I found from the doctors here I will forever be grateful for! Don’t hesitate to trust them in your health journey too! Thank you Aspen!
Taylor F
24 February 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Dr. Paul Despres has literally changed my life! I had horrible undiagnosed gut issues, and after meeting with two gastroenterologists that were not able to diagnose the problem, I found Dr. Paul. He put me on a regimen of supplements to help me with my gut, and proceeded to work with me also on vitamin deficiencies and my osteoporosis. The result has been a complete reduction of all gut symptoms (turned out I had SIBO), and a significantly better energy level and quality of life thanks to Dr. Paul. A special shout out to his lovely and competent assistant Jane. She is whip smart and always responsive. I highly recommend Aspen Integrative Medical Center.
Kim M
18 February 2025
Google star 1Google star 2Google star 3Google star 4Google star 5
Dr. Alexandra Mele is amazing! I have been seeing her for almost a year now for craniosacral therapy. I would highly recommend.
Morgan A
28 January 2025
Aspen Integrative Medical Center location icon
Convenient Location

Located in downtown Flagstaff, Aspen Integrative Medical Center is a convenient location for people looking for naturopathic care in Northern Arizona.

parking sign icon
Ease of Access

With both a private lot and street parking available, you'll always find a good place to park. We're also handicap accessible, so making it in for treatment is a breeze.

Our clinic, front recepetion - desk icon
Front Reception

Our staff goes above and beyond to ensure you have a smooth experience—not just before seeing our physicians, but also as you leave with a clear understanding of your next steps. Our front desk team is trusted, timely, and supportive every step of the way.

Intravenous therapy, IV therapy icon
IV Suite

Our IV room is spacious and comfortable. Whether you're working, reading, or having a nap, it'll be easy to pass the time while receiving your IV.

Experience our one-of-a-kind medical clinic for yourself.